Gelosia: individuata l’area del cervello responsabile della ‘sindrome di Otello’ – Hardwired for Jealousy…

Lo studio dei ricercatori dell’Università di Pisa pubblicato su una rivista della Cambridge University Press. La gelosia delirante a cui sono associati comportamenti aggressivi come lo stalking, il suicidio o l’omicidio sarebbe legata ad uno squilibrio di una specifica area del cervello. E’ questo il risultato di uno studio condotto da un team di ricercatori del Dipartimento di Medicina Clinica e Sperimentale dell’Università di Pisa e recentemente pubblicato sulla rivista CNS Spectrums della Cambridge University Press. Secondo gli autori dell’articolo – Donatella Marazziti, Michele Poletti, Liliana Dell’Osso, Stefano Baroni e Ubaldo Bonuccelli – le radici neuronali della cosiddetta “sindrome di Otello” si troverebbero nella corteccia frontale ventro-mediale, un’area del cervello che sovrintende complessi processi cognitivi e affettivi. “Abbiamo elaborato un modello teorico – spiega Donatella Marazziti – basato sull’osservazione clinica dei pazienti affetti da schizofrenia, alcolismo e morbo di Parkinson nei quali sono molto comuni le manifestazioni di gelosia delirante, in particolare nei soggetti che soffrono di morbo di Parkinson e che sono curati con farmaci che incrementano la produzione di dopamina”. “L’indagine empirica delle basi neurali della gelosia è solo all’inizio e ulteriori studi sono necessari per chiarirne le radici biologiche”, avverte Donatella Marazziti. Se infatti la gelosia è un sentimento del tutto

naturale, il punto è individuare lo squilibrio biochimico che trasforma questo sentimento in un’ossessione pericolosa. Pensare che la relazione con la persona amata sia l’unica cosa importante della propria vita, interpretare erroneamente i comportamenti e i sentimenti del partner e percepire la sua perdita come una totale catastrofe sono ad esempio sintomi che alla fine possono portare a comportamenti aggressivi ed estremi.”La speranza – conclude Donatella Marazziti – è che una maggiore conoscenza dei circuiti cerebrali e delle alterazioni biochimiche che sottendono i vari aspetti della gelosia delirante, possa aiutare ad arrivare ad un’identificazione precoce dei soggetti a rischio”. – Hardwired for jealousy. Stalkers’ brains could be programmed for obsession, new research shows: he brains of the obsessively jealous are specially programmed to generate their out of control behavior, says a new study. Understanding how the brains of stalkers function could lead to medication to control extreme forms of jealous behavior. A team of researchers from the Departments of Neuroscience and Psychiatry at the University of Pisa, Italy, claim they have discovered the areas of the brain responsible for making us jealous and of triggering the kind of delusional jealousy that drives stalkers – also known as Othello’s syndrome after the Shakespeare character who kills his wife due to jealousy. The researchers are keen to widen their research to examine the areas of the brain associated with being in love to see how these connect to the jealousy centers. In a new article in the journal CNS Spectrums, which is published by Cambridge University Press, the researchers examined MRI brain scans and trawled through research into neurological and psychiatric disorders that are accompanied by delusional jealousy to reach their conclusions. While acknowledging that jealousy is a fundamental of human experience, the authors sought to pinpoint what is happening in the brain when jealousy turns into a dangerous obsession that may result in extremely aggressive

behavior, such as stalking, suicide, or murder.The neural roots of jealousy are located in the area of the brain called the ventromedial prefrontal cortex, which is found roughly just above the forehead. In this region we process emotions and reflect on ourselves and others. Here we process thoughts and feelings of the one we love and predict scenarios of how we would feel about his or her possible loss.The obsessively jealous brain appears to have three characteristics: it is prone to believe the relationship with the loved one is the only thing of any importance; it misinterprets innocent behaviors, thoughts, and feelings of the loved one; and it feels the potential loss of the loved one as a life-shattering catastrophe. This in turn can prompt extreme reactions like stalking or even murder. The researchers believe that, in some people, this process may become ingrained, leading to a destructive ‘habit’ of jealousy becoming hardwired in the brain. They want to do more research on this aspect and also investigate how medication can help.The brain dimension could also explain why extreme delusional forms of jealousy are common in psychiatric disorders such as schizophrenia and alcoholism, and also in neurological disorders such as Alzheimer’s and Parkinson’s.Team researcher Donatella Marazziti said the study of jealousy is just beginning: “Jealousy has long attracted the interest of both psychiatrists and psychologists, but it is only recently that it has captured the attention of neuroscience – the science of the nervous system including the brain. It has also been ‘hidden’ in wider classifications of disorders such as depression, obsessive-compulsive disorder or paranoia. Our research shows that it really deserves a category of its own – especially in its extreme forms when it provokes terrifying behaviors such as stalking or drives people to suicide or murder.” Marazziti continued, “The study of the roots of jealousy in the brain is just beginning. Ultimately we would like to be able to understand it well enough to be able to control its more extreme forms. However, much more work needs to be done to understand the biological roots of this emotion that still represents a great mystery of human nature.” (Cambridge University Press’ Press Release)


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