Coffee linked to reduced risk of stroke

Women who drink one cup of coffee or more a day have a 22 to 25 percent lower risk of getting a stroke, according to a new study from Karolinska Institutet. The study, published in the scientific journal Stroke, was based on data from 34,670 women aged 49 to 83. The women in the study were followed for about 10 years, and were using a self-administered questionnaire about their coffee-drinking habits. The findings also suggest that low or no coffee consumption is associated with an increased risk of stroke in women. The researchers at the Institute of Environmental Medicine note that it is too early to give any recommendations about changed coffee-drinking habits. The findings should, however, ease the concerns of some women. Coffee is one of the most widely consumed beverages in the world. Therefore, even small health effects of substances in coffee may have large public health consequences.  –  Prof. Susanna C. Larsson. Division of Nutritional Epidemiology. Description of Projects and Results. My research focuses primarily on examining dietary and lifestyle factors in relation to risk of cancer and cardiovascular disease. This research is mainly based on data from two large prospective cohort studies: the Swedish Mammography Cohort (61,000 women) and the Cohort of Swedish Men (45,000 men). Examples of research findings on diet and colorectal cancer include positive associations with intakes of red meat and heme iron and decreased risks with greater intakes of dietary folate, vitamin B6, magnesium,

calcium, conjugated linoleic acid, dairy foods, and whole grains. In addition, we have found protective associations with higher physical activity and long-term aspirin use. With regard to pancreatic cancer we have observed increased risks with cigarette smoking, obesity, and diabetes as well as with high consumption of red meat, sugar, and soft drinks. We have found a reduced risk of pancreatic cancer associated with high intakes of folate and methionine, both of which are important dietary methyl group donors involved in DNA synthesis and DNA methylation. For gastric cancer, we have observed inverse associations with intakes of fruits and vegetable, carotenoids, retinol, and vitamin A and an increased risk associated with high consumption of processed meat. Other selected findings include inverse associations between coffee consumption and risk of liver cancer and between magnesium intake and risk of type 2 diabetes. – The Institute of Environmental Medicine, a department at Karolinska Institutet, is an interdisciplinary research organization within the field of Environmental Medicine. Within the Institute, internationally competitive research in the fields of toxicology, environmental medicine and epidemiology is conducted. The Institute of Environmental Medicine (IMM). News from: Karolinska Institutet Stockholm, Sweden

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